Oakstone Samuels Comprehensive Review of Neurology 2026

Comprehensive Neurology Review for Modern Clinical Practice

Samuels Comprehensive Review of Neurology 2026 is a comprehensive online CME program designed to strengthen the diagnostic, clinical reasoning, and management skills of neurologists, neurology trainees, and neurosurgery residents. Building upon the renowned educational legacy of Dr. Martin A. Samuels, this intensive review delivers a broad and practical exploration of both common and complex neurological disorders encountered in modern clinical practice.

Featuring more than 60 expert-led lectures, the program provides an evidence-based review of neurological disease mechanisms, diagnostic approaches, localization strategies, differential diagnosis development, treatment planning, prognostication, and long-term patient management. Participants gain practical insights that can be immediately applied in outpatient clinics, hospital settings, emergency neurology, and subspecialty practice.

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Course Overview

Neurologic disorders remain among the leading causes of disability and mortality worldwide. Accurate diagnosis often requires careful clinical reasoning, detailed history-taking, comprehensive neurologic examination, and precise localization of pathology within the nervous system.

This comprehensive review course helps clinicians refine these essential skills while staying current with modern diagnostic criteria, advanced neuroimaging techniques, guideline-based treatments, and evolving therapeutic options. Through a structured and systematic approach, participants develop greater confidence in evaluating challenging neurologic presentations and implementing effective patient-centered management strategies.

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Included Content

• 66 High-Quality Video Lectures
• 2 Comprehensive PDF Resources
• Expert Faculty Presentations
• Evidence-Based Clinical Reviews
• Case-Based Learning Discussions
• Practical Diagnostic Frameworks

Total Size: 16.26 GB

Date of Original Release: April 30, 2026

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Comprehensive Curriculum

Foundations of Neurologic Diagnosis

Participants review the essential principles of:

• Neurologic history taking
• Neurologic examination
• Lesion localization
• Differential diagnosis development
• Clinical reasoning
• Diagnostic decision-making
• Neurologic emergencies

Special emphasis is placed on translating clinical findings into accurate diagnoses.

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Cerebrovascular Disorders

Comprehensive coverage includes:

• Ischemic stroke
• Hemorrhagic stroke
• Transient ischemic attacks
• Cerebral venous thrombosis
• Stroke prevention
• Acute stroke management
• Secondary prevention strategies

Faculty review current guidelines and advances in stroke care.

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Epilepsy and Seizure Disorders

Topics include:

• Seizure classification
• Epilepsy syndromes
• Diagnostic evaluation
• EEG interpretation principles
• Anti-seizure medications
• Status epilepticus
• Surgical treatment options

Participants learn modern approaches to seizure diagnosis and management.

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Headache Medicine

Sessions explore:

• Migraine disorders
• Chronic migraine
• Cluster headaches
• Trigeminal autonomic cephalalgias
• Secondary headache syndromes
• Preventive therapies
• Emerging migraine treatments

Practical management strategies are emphasized throughout.

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Neurodegenerative Disorders

Extensive review includes:

• Alzheimer’s disease
• Parkinson’s disease
• Lewy body dementia
• Frontotemporal dementia
• Atypical parkinsonian syndromes
• Cognitive impairment
• Dementia evaluation

Participants learn current diagnostic and treatment approaches.

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Movement Disorders

Coverage includes:

• Tremor disorders
• Dystonia
• Chorea
• Ataxia
• Functional movement disorders
• Parkinsonian syndromes
• Deep brain stimulation principles

Faculty discuss both medical and procedural therapies.

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Multiple Sclerosis and Neuroimmunology

Topics include:

• Multiple sclerosis
• Neuromyelitis optica
• MOG-associated disease
• Autoimmune encephalitis
• CNS inflammatory disorders
• Disease-modifying therapies
• Immunologic treatment strategies

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Neuromuscular Disorders

Participants review:

• Peripheral neuropathies
• Myopathies
• Neuromuscular junction disorders
• Myasthenia gravis
• ALS
• Muscular dystrophies
• Electrodiagnostic evaluation

Practical approaches to diagnosis and treatment are highlighted.

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Neuro-Oncology

Coverage includes:

• Primary brain tumors
• Metastatic brain disease
• Spinal tumors
• Paraneoplastic neurologic syndromes
• Treatment complications
• Multidisciplinary management

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Sleep Medicine

Sessions discuss:

• Sleep disorders
• Obstructive sleep apnea
• Narcolepsy
• Parasomnias
• Restless legs syndrome
• Sleep-related neurologic conditions

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Neurocritical Care

Participants explore:

• Neurologic emergencies
• Increased intracranial pressure
• Status epilepticus
• Acute neuromuscular respiratory failure
• Critical care management principles

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Spine and Peripheral Nervous System Disorders

Topics include:

• Radiculopathies
• Myelopathies
• Spinal cord disorders
• Entrapment neuropathies
• Degenerative spine disease

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Special Topics in Neurology

Additional discussions include:

• Functional neurologic disorders
• Neurogenetics
• Women’s neurologic health
• Neurology in aging populations
• Neurologic complications of systemic disease
• Social determinants of neurological health

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Learning Objectives

Upon completion of this activity, participants will be able to:

• Evaluate neurologic symptoms using systematic clinical assessment methods.
• Apply neurologic localization principles to improve diagnostic accuracy.
• Utilize appropriate diagnostic testing for suspected neurologic disorders.
• Differentiate disorders with overlapping clinical presentations.
• Integrate current evidence and guideline-based recommendations into practice.
• Develop effective treatment strategies for common and complex neurologic diseases.
• Recognize clinical warning signs requiring urgent evaluation or specialist intervention.
• Incorporate patient-specific factors into individualized care plans.
• Improve clinical reasoning and diagnostic confidence.
• Enhance patient outcomes through evidence-based neurologic management.

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Educational Features

✔ 66 Expert-Led Neurology Lectures

✔ Comprehensive Neurology Review

✔ Case-Based Learning

✔ Evidence-Based Clinical Practice

✔ Diagnostic Localization Strategies

✔ Differential Diagnosis Development

✔ Treatment and Management Updates

✔ Neurology Board Review Resource

✔ Practical Clinical Applications

✔ Online On-Demand Access

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Target Audience

This course is designed for:

• Neurologists
• Neurology Residents
• Neurology Fellows
• Neurosurgery Residents
• Neurohospitalists
• Stroke Specialists
• Epileptologists
• Movement Disorder Specialists
• Neurocritical Care Physicians
• Internal Medicine Physicians with Neurology Interest
• Advanced Practice Providers in Neurology

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Why This Course Matters

Neurologic diagnosis remains one of the most intellectually demanding areas of medicine, requiring precise clinical observation, advanced reasoning, and integration of rapidly evolving evidence. Samuels Comprehensive Review of Neurology 2026 provides a structured, high-yield review of the full spectrum of neurologic disease while strengthening practical skills in diagnosis, localization, management, and long-term patient care.

Whether preparing for board examinations, updating clinical knowledge, or refining day-to-day practice, this program delivers a thorough and clinically relevant review that supports excellence in neurologic care.

+ Topics:

Cognitive and Behavioral Neurology

• Evaluation of Cognitive Disorders and Dementia – Kirk R. Daffner, MD
• Alzheimer’s Disease – Alireza Atri, MD, PhD
• Rapidly Progressive Dementias and Encephalopathies – Scott McGinnis, MD
• Neuropsychiatry Essentials – Bridging Brain and Behavior – Haythum Tayeb, MBChB
• Preventive Brain Care and Brain Health – Jonathan Rosand, MD, PhD

Movement Disorders

• Parkinson’s Disease: Medical Treatment – Albert Hung, MD, PhD
• Neurosurgical Management of Parkinson’s Disease – Vishad Sukul, MD
• Hyperkinetic Movement Disorders – Edison K. Miyawaki, MD
• Functional Movement Disorders – Shilpa Chitnis, MD, PhD, FAAN
• Ataxia – Vikram Shakkottai, MD, PhD
• The Differential Diagnosis of Atypical Parkinsonian Disorders – Katherine Amodeo, MD
  

Stroke

• Prevention of Stroke – Steven K. Feske, MD
• Treatment of Acute Ischemic Stroke – Gurmeer Kaur, MD
• Management of Hemorrhagic Stroke – Matthew B. Bevers, MD, PhD
• Challenging Neurovascular Cases – from PFO Closure to Complex Decision-Making – Ji Chong, MD
• Redefining Stroke Intervention – Late-Window Thrombectomy and Future Innovations – Fawaz Al-Mufti, MD, FAHA, FSVIN
• Neurorecovery After Stroke – Virtual Reality, Robotics, and Neuromodulation – Tomoko Kitago, MD

Hospital Neurology

• Acute Neurology in the Hospital Setting – from Bedside to Discharge – Adam Karp, MD
• Principles of Neurocritical Care – Stephan A. Mayer, MD
  
• Neuroprognostication After Cardiac Arrest – David Greer, MD, MA

Neuromuscular Disorders

• Amyotrophic Lateral Sclerosis (ALS) – Diagnosis and Treatment – Laura Rosow, MD
  
• Approach to Neuropathy – Christopher Doughty, MD
• Entrapment Neuropathies – David C. Preston, MD
• Clinical Approach to Myopathies and Neuromuscular Junction Disorders – Anthony A. Amato, MD
• Gene Therapy and RNA-Based Treatments in Neuromuscular Diseases – Vijay Ganesh, MD

Multiple Sclerosis

• Multiple Sclerosis – Stephanie Gandelman, MD
• NMO and MOG – Everything a Neurologist Needs to Know – Michael Levy, MD, PhD
• Emerging Autoimmune and Systemic Inflammatory Neurologic Disorders – Giovanna Manzano, MD

Sleep Disorders

• Sleep Disorders – Michael H. Silber, MBChB

Epilepsy

• Medical Treatment of Epilepsy – Manish G. Holmes, MD, FAES
• Non-Pharmacologic Treatments for Epilepsy – Ellen J. Bubrick, MD, FAES
• Status Epilepticus – Jong Woo Lee, MD, PhD
• Sudden Unexpected Death in Epilepsy (SUDEP) – Daniel Friedman, MD, MSc
• Epilepsy in the Older Adult – Alice D. Lam, MD, PhD

Neuro-Ophthalmology

• Disorders of Vision – Daniel Schwartz, MD
• Disorders of Pupils and Eye Movements – Sashank Prasad, MD

Neuro-Otology

• Evaluation and Management of Dizziness and Vertigo – Katrina Stidham, MD

Pain

• Headache – Angeliki Vgontzas, MD
• Trigeminal Neuralgia and Facial Pain – Lauren Levi, DMD, MS
• Local Nerve Blocks for Pain – Nitin K. Sekhri, MD
• Low Back Pain – Nitin K. Sekhri, MD

Neurology of Systemic Diseases

• Autoimmune Encephalitis and Paraneoplastic Syndromes – Sarah Parauda, MD
• Neurological Manifestations of Electrolyte Disorders – Robert Laureno, MD
• Frightened to Death – The Modern Lessons of Neurocardiology – Martin A. Samuels, MD

Cancer Neurology

• Primary Brain Tumors – Luis Nicolas Gonzalez-Castro, MD, PhD
• Metasteses to the Nervous System – J. Ricardo McFaline-Figueroa, MD, PhD
• Neurological Aspects of Systemic Cancer – Amy A. Pruitt, MD
• Catch-22 – Neurotoxicity from Checkpoint Inhibition and CAR-T – Alec Friedman, MD

Neurological Infectious Disease

• Neurological Infectious Diseases – Karen L. Roos, MD

Coma and Disorders of Consciousness

• Coma and Other Disorders of Consciousness – Brian L. Edlow, MD

Special Topics

• Neurology of Alcohol – Michael E. Charness, MD
• Neurology of Substance Use Disorders – Lauren Augello, MD
• Palliative Care of the Neurological Patient – Mara Lugassy, MD
• Contemporary Issues in Women’s Neurology – Mary A. O’Neal, MD, FAAN
  
• Sports Neurology – Concussion Care and Beyond – Claus Reinsberger, MD, PhD
• Step-by-Step Diagnosis and Treatment of Functional Neurological Disorders – Seizures/Attacks – Barbara A. Dworetzky, MD
• Global Neurology – Challenges and Innovations Across Borders – Aaron L. Berkowitz, MD, PhD
  
• Neurology at the Intersection of Law and Policy – Capacity, Driving, and Decision Making – Benjamin Tolchin, MD, MS, HEC-C, FAAN, FAES
• How Neurologists Think – What My Mistakes Taught Me – Martin A. Samuels, MD
• Structural and Social Determinants of Neurological Disorders – Mill Etienne, MD
• Advanced Neurologic Examination Pearls – Beyond Textbooks – Tracey A. Milligan, MD, MS, FAAN, FAES, FANA
• Artificial Intelligence in Neurology – Promise and Pitfalls – Erik Tarula, MD
• Neuroimaging for the Clinician – Practical Applications Across Neurology – Joshua P. Klein, MD, PhD
• Updates in Neurotherapeutics – What’s New and What’s Next – Tracey A. Milligan, MD, MS, FAAN, FAES, FANA