Cytopathology: Masters of Pathology Series 2026 (Videos + PDF)
Master Modern Cytopathology Through Practical, Case-Based Learning
Cytopathology: Masters of Pathology Series 2026 is a comprehensive educational program designed to provide pathologists, cytopathologists, pathology trainees, and laboratory professionals with an up-to-date review of contemporary cytopathology practice. As part of the renowned Masters of Pathology Series, this course combines expert-led lectures, real-world case discussions, and evidence-based diagnostic strategies to strengthen confidence and accuracy in cytologic interpretation.
Designed for both experienced practitioners and those with limited formal training in cytopathology, this program focuses on practical diagnostic approaches, specimen-specific reporting systems, molecular pathology applications, and common pitfalls encountered in daily practice. Participants will gain valuable insight into the evolving role of ancillary testing and how modern molecular techniques are transforming the diagnosis and management of disease using minimally invasive specimens.
Through concise, high-yield presentations organized by specimen type, learners develop a structured approach to cytologic evaluation while improving communication with clinicians through standardized reporting systems.
Course Overview
Cytopathology plays a critical role in modern patient care by providing rapid, minimally invasive diagnostic information across a broad spectrum of diseases. Advances in molecular diagnostics, risk stratification systems, and reporting guidelines have significantly enhanced the accuracy and clinical utility of cytologic interpretation.
This course provides a comprehensive review of current cytopathology practice, emphasizing practical diagnostic decision-making and effective utilization of ancillary studies. Participants learn how to recognize benign, reactive, atypical, and malignant findings while understanding the strengths and limitations of cytology specimens in various clinical settings.
Special attention is given to contemporary WHO classifications, Bethesda reporting systems, and other standardized diagnostic frameworks that improve communication between pathologists and treating clinicians.
Comprehensive Curriculum
Thyroid Cytopathology
A detailed review of thyroid fine needle aspiration (FNA) interpretation, including:
- The Bethesda System for Reporting Thyroid Cytopathology
- Benign thyroid nodules
- Follicular lesions
- Atypia of undetermined significance (AUS)
- Follicular neoplasms
- Suspicious thyroid lesions
- Papillary thyroid carcinoma
- Medullary thyroid carcinoma
- Molecular testing in thyroid nodules
- Risk stratification and clinical management
Participants learn how standardized reporting has reduced unnecessary thyroid surgery while improving patient outcomes.
Cervical Cytology
Comprehensive coverage includes:
- Cervical cancer screening
- Human papillomavirus (HPV) testing
- Bethesda reporting terminology
- Squamous intraepithelial lesions
- Glandular abnormalities
- Cervical dysplasia
- Cytologic-histologic correlation
- Screening challenges and pitfalls
The course reviews contemporary cervical screening strategies and diagnostic criteria.
Pulmonary Cytopathology
Topics include:
- Lung cancer diagnosis
- Bronchial specimens
- Fine needle aspiration cytology
- Small cell carcinoma
- Non-small cell lung carcinoma
- Molecular testing for targeted therapy
- Biomarker assessment
- Cytologic diagnosis of pulmonary lesions
Participants learn how cytology supports precision medicine in thoracic oncology.
Salivary Gland Cytopathology
Coverage includes:
- The Milan System for Reporting Salivary Gland Cytopathology
- Benign salivary gland lesions
- Inflammatory disorders
- Salivary gland neoplasms
- Diagnostic categories and risk assessment
- Ancillary testing applications
Faculty discuss practical approaches to difficult salivary gland specimens.
Pancreaticobiliary Cytopathology
Participants review:
- Pancreatic cysts
- Solid pancreatic tumors
- Endoscopic ultrasound-guided FNA
- Pancreatic adenocarcinoma
- Neuroendocrine tumors
- Biliary tract lesions
- Molecular diagnostics
Special emphasis is placed on integrating cytology with clinical and radiologic findings.
Lymph Node Cytopathology
Topics include:
- Reactive lymphoid proliferations
- Lymphoma diagnosis
- Metastatic disease
- Flow cytometry
- Immunophenotyping
- Ancillary studies
- Diagnostic algorithms
The course highlights practical approaches for evaluating lymphoid specimens.
Urinary Cytopathology
Coverage includes:
- The Paris System for Reporting Urinary Cytology
- Urothelial carcinoma
- Reactive urothelial changes
- Atypical urinary specimens
- Risk-based reporting
- Diagnostic pitfalls
Participants gain confidence in urinary cytology interpretation and reporting.
Breast Cytopathology
Topics include:
- Fine needle aspiration techniques
- Benign breast lesions
- Fibroadenoma
- Cystic lesions
- Breast carcinoma
- Triple assessment correlation
- Ancillary testing
Faculty review the role of cytology in breast lesion evaluation.
Molecular Pathology and Ancillary Testing
Modern cytopathology increasingly relies on advanced ancillary studies.
This course explores:
Molecular Testing
- Next-generation sequencing (NGS)
- Mutation analysis
- Gene fusion testing
- Targeted therapy biomarkers
- Precision oncology applications
Immunocytochemistry
- Diagnostic marker selection
- Differential diagnosis support
- Tumor classification
- Prognostic markers
Additional Ancillary Studies
- Flow cytometry
- Fluorescence in situ hybridization (FISH)
- Microbiologic testing
- Special stains
- Cell block preparation
Participants learn how to appropriately integrate ancillary studies into cytologic diagnosis.
Diagnostic Pitfalls and Challenges
One of the major strengths of this course is its focus on avoiding common diagnostic errors.
Topics include:
- Overinterpretation of benign findings
- Reactive atypia versus malignancy
- Sampling limitations
- False-positive diagnoses
- False-negative diagnoses
- Cytology-histology discordance
- Difficult differential diagnoses
- Quality assurance strategies
Expert faculty share practical pearls gained through years of diagnostic experience.
Standardized Reporting Systems
The course reviews current reporting frameworks that improve diagnostic consistency and clinician communication, including:
- Bethesda System for Thyroid Cytopathology
- Bethesda System for Cervical Cytology
- Milan System for Salivary Gland Cytopathology
- Paris System for Urinary Cytology
- WHO Classification Updates
Participants learn how standardized reporting supports evidence-based clinical management.
Learning Objectives
Upon completion of this course, participants will be able to:
- Apply current reporting systems to cytopathology specimens.
- Recognize benign, reactive, atypical, and malignant cytologic findings.
- Improve diagnostic accuracy using structured interpretation methods.
- Integrate molecular testing and ancillary studies into cytologic diagnosis.
- Avoid common pitfalls in cytopathology practice.
- Utilize evidence-based approaches for specimen interpretation.
- Correlate cytologic findings with clinical and histologic data.
- Generate clear, standardized reports that support clinical decision-making.
- Understand the evolving role of precision medicine in cytopathology.
- Enhance communication between pathologists and treating clinicians.
Educational Features
✔ Expert-Led Cytopathology Lectures
✔ Videos + Comprehensive PDF Materials
✔ Specimen-Based Learning Structure
✔ WHO Classification Updates
✔ Bethesda Reporting Systems
✔ Milan and Paris Reporting Systems
✔ Molecular Pathology Applications
✔ Immunocytochemistry Guidance
✔ Real-World Diagnostic Cases
✔ Practical Reporting Strategies
✔ Common Pitfalls and Diagnostic Pearls
✔ Evidence-Based Cytopathology Practice
Target Audience
This course is ideal for:
- Cytopathologists
- General Pathologists
- Surgical Pathologists
- Pathology Residents
- Pathology Fellows
- Laboratory Directors
- Cytotechnologists
- Molecular Pathologists
- Academic Faculty
- Medical Laboratory Professionals
- Healthcare Providers Interested in Diagnostic Pathology
Why This Course Stands Out
Cytopathology: Masters of Pathology Series 2026 delivers a practical and highly relevant review of contemporary cytopathology. By combining specimen-specific instruction, standardized reporting systems, molecular diagnostics, ancillary testing, and real-world case discussions, the course equips participants with the skills needed to confidently interpret cytology specimens in modern clinical practice.
Whether reviewing thyroid FNAs, pulmonary specimens, salivary gland lesions, urinary cytology, or complex cytology-histology discrepancies, participants gain the knowledge and confidence necessary to improve diagnostic precision and patient care.
Topics / Speakers
- The Bethesda System for Reporting Thyroid Cytopathology Third Edition – Paul A. VanderLaan, MD, PhD
- Molecular Testing in Thyroid FNA Specimens – Michiya Nishino, MD, PhD
- Thyroid Cytomorphology Part I – Christopher J. VandenBussche, MD, PhD
- Thyroid Cytomorphology Part II – Christopher J. VandenBussche, MD, PhD
- Instructive Thyroid FNA Cases – Christopher J. VandenBussche, MD, PhD
- The Milan System for Reporting Salivary Gland Cytopathology Second Edition – William C. Faquin, MD, PhD
- Instructive Salivary Gland FNA Cases – Zahra Maleki, MD
- FNA of Lateral Neck Lesions – A Case-Based Approach – Darcy A. Kerr, MD
- Approach to Liver Cytopathology and Small Biopsies – M. Lisa Zhang, MD
- Update on the WHO Reporting System for Pancreaticobiliary Cytopathology – Martha Bishop Pitman, MD
- FNA Cytology of Solid Pancreatic Lesions – Monica T. Garcia-Buitrago, MD, FCAP
- Approach to Pancreatic Cyst Cytology – M. Lisa Zhang, MD
- Instructive Pancreas FNA Cases – Christopher J. VandenBussche, MD, PhD
- Serous Cavity I – The International System for Serous Fluid Cytopathology – Ashish Chandra, FRCPath, DipRCPath (Cytol)
- Serous Cavity II – Pleural Fluid – Malignant Tumors and Mimickers – Peter Illei, MD
- Serous Cavity III – Pelvic Washing Specimens – Christopher J. VandenBussche, MD, PhD
- Serous Cavity IV – Challenges Cases – Pelvic Washing Specimens – Christopher J. VandenBussche, MD, PhD
- Bone and Soft Tissue (BST) I – The WHO Reporting System for Soft Tissue Cytopathology – Ivan Chebib, MD, FRCPC
- Bone and Soft Tissue (BST) II – A Pattern-Based Approach – Vickie Y. Jo, MD
- Bone and Soft Tissue (BST) III – An Update on Immunohistochemical Markers – Vickie Y. Jo, MD
- Cytopathology of Bone Tumors – Valerie A. Fitzhugh, MD
- Cytopathology of Soft Tissue Tumors – Valerie A. Fitzhugh, MD
- The International System for Reporting Lung Cytopathology – Fernando Schmitt, MD, PhD, FIAC
- Pulmonary I – Cytology of NSCLC – Does Morphology Matter? – Peter Illei, MD
- Pulmonary II – Lung Tumors other than NSCLC – Peter Illei, MD
- Pulmonary III – Ancillary Testing in NSCLC: Why, When, and How to Perform? – Peter Illei, MD
- Pulmonary IV – Non-Neoplastic Pulmonary Cytology: Bugs, BALs, and Beyond – Peter Illei, MD
- Kidney I – Fine Needle Aspiration and Small Biopsy Specimens – Madelyn Lew, MD
- Kidney II – Fine Needle Aspiration and Small Biopsy Specimens – Madelyn Lew, MD
- Breast I – Introduction to the Yokohama System – Gary Tse, MBBS
- Breast II – Challenging Cases in Breast Cytology – Christine Noga Booth MD
- Urine I – The Paris System for Reporting Urinary Cytology – Christopher J. VandenBussche, MD PhD
- Urine II – Benign and Reactive Findings in Urine Specimens – Christopher J. VandenBussche, MD PhD
- Urine III – Neoplastic Findings in Urine Specimens – Christopher J. VandenBussche, MD PhD
- Urine IV – Instructive Urine Cytology Cases – Madelyn Lew, MD
- Miscellaneous FNA Challenge Cases – Christopher J. VandenBussche, MD PhD
- HPV Biology and Testing in Pap Test Specimens – Michael J. Thrall, MD
- ASCCP Guidelines and the Role of Cytology in Screening – Michael J. Thrall, MD
- Pap Test Cytomorphology I – Squamous Lesions – Donna K. Russell, MEd, CT(ASCP)HT, CFIAC
- Pap Test Cytomorphology II – Glandular and Rare Lesions – Donna K. Russell, MEd, CT(ASCP)HT, CFIAC
- Instructive Pap Test Cases – Donna K. Russell, MEd, CT(ASCP)HT, CFIAC
- Cerebrospinal Fluid and Vitreous Fluid Specimens – Cheng-Ying Ho, MD, PhD
- Lymph Node Cytology – A Case Based Approach in Small Biopsies of Lymph Nodes – Sara E. Monaco, MD



