UW Medicine 2nd International Symposium on Merkel Cell Carcinoma 2022

(MCC) is designed to explore emerging data that may allow improvements in understand the basic biology that drives this disease, clinical guidelines, and to develop innovative approaches. Updates from the most recent clinical guidelines as well as emerging data regarding MCC biology are highlighted in plenary sessions. The educational purpose of this symposium is to disseminate emerging data and to advance MCC research through a stimulating and collaborative meeting.

The need for clinicians to continuously stay abreast of developments and current standards of care in the field of MCC is challenging because it is so rapidly evolving. Many clinicians are not familiar with how MCC differs from other skin cancers in its optimal management.

This activity will offer comprehensive reviews of the established standards of care and recent clinical advances in the field of MCC management, national cancer guidelines, and treatment recommendations in various clinical settings.

1. Address the outstanding questions in MCC basic biology and how they can lead to improvements in clinical care.
2. Identify the current clinical MCC biomarkers of disease burden and how to interpret those.
3. Review and discuss the updated national MCC clinical guidelines.

WHO SHOULD ATTEND
Healthcare providers including MDs, DOs, PhDs, other healthcare professionals, and scientists interested in MCC.

 Topics:

• ‘Immunotherapy for solid organ transplant recipients with advanced MCC and other skin cancers.mp4
• ‘Immunotherapy for solid organ transplant recipients with advanced MCC and other skin cancers.pdf
• Ablative Radiation Therapy for Merkel Cell Carcinoma.mp4
• Ablative Radiation Therapy for Merkel Cell Carcinoma.pdf
• Abstract- Development of a Merkel polyomavirus-specific T cell receptor analysis tool to guide cancer immunotherapy.mp4
• Abstract- Development of a Merkel polyomavirus-specific T cell receptor analysis tool to guide cancer immunotherapy.pdf
• Abstract- Impact of duration of immunotherapy on clinical outcomes in advanced Merkel cell carcinoma patients responding to first-line immunotherapy.mp4
• Abstract- Impact of duration of immunotherapy on clinical outcomes in advanced Merkel cell carcinoma patients responding to first-line immunotherapy.pdf
• Abstract- MCPyV ALTO is silenced in -virus-positive Merkel cell carcinoma and suppresses tumorigenesis.pdf
• Abstract- Merkel polyoma virus specific transgenic T cell receptor therapy in PD-1 inhibitor refractory Merkel cell carcinoma.mp4
• Abstract- Merkel polyoma virus specific transgenic T cell receptor therapy in PD-1 inhibitor refractory Merkel cell carcinoma.pdf
• Abstract- Real-world assessment of ipilimumab plus nivolumab in anti-PD-L1 PD-1- refractory Merkel 1 Cell Carcinoma.mp4
• Abstract- Real-world assessment of ipilimumab plus nivolumab in anti-PD-L1 PD-1- refractory Merkel 1 Cell Carcinoma.pdf
• Abstract- The paranuclear dot in Merkel cell carcinoma, how does it form and what does it do..mp4
• Abstract- The paranuclear dot in Merkel cell carcinoma, how does it form and what does it do..pdf
• Animal Models of MCC.mp4
• Animal Models of MCC.pdf
• AST-008 and TLR9 agonists in Merkel cell carcinoma.mp4
• AST-008 and TLR9 agonists in Merkel cell carcinoma.pdf
• Avelumab in mMMC- real-world data.mp4
• Avelumab in mMMC- real-world data.pdf
• Can we harness T-cells specific for Merkel cell polyomavirus with therapuetic vaccination..mp4
• Can we harness T-cells specific for Merkel cell polyomavirus with therapuetic vaccination..pdf
• Clues to the Origins of Merkel Cell Carcinoma.mp4
• Clues to the Origins of Merkel Cell Carcinoma.pdf
• Contribution of Merkel Cell Polyomavirus to Merkel Cell Carcinoma.mp4
• Contribution of Merkel Cell Polyomavirus to Merkel Cell Carcinoma.pdf
• Cross-sectional Imaging In Merkel Cell Carcinoma- Is Less More..mp4
• Cross-sectional Imaging In Merkel Cell Carcinoma- Is Less More..pdf
• Diagnostic Yield of Staging Brain MRI in Merkel Cell Carcinoma.mp4
• Diagnostic Yield of Staging Brain MRI in Merkel Cell Carcinoma.pdf
• Epigenetic and Genetic Determinants of Merkel Cell Carcinoma.mp4
• Epigenetic and Genetic Determinants of Merkel Cell Carcinoma.pdf
• Featured Abstract- Virally mediated mechanisms of HLA class I loss in Merkel cell carcinoma and implications for viral epitope presentation.mp4
• Featured Abstract- Virally mediated mechanisms of HLA class I loss in Merkel cell carcinoma and implications for viral epitope presentation.pdf
• Immunotherapy Platform and Related-omics.mp4
• Immunotherapy Platform and Related-omics.pdf
• MCC Immunotherapy- Lessons Learnt and Unmet Needs.mp4
• MCC Immunotherapy- Lessons Learnt and Unmet Needs.pdf
• MCPyV-specific T cell discovery for adoptive T cell therapy.mp4
• MCPyV-specific T cell discovery for adoptive T cell therapy.pdf
• Mechanisms of Oncogenesis- MCC Cell of Origin.mp4
• Mechanisms of Oncogenesis- MCC Cell of Origin.pdf
• Merkel Cell Carcinoma in France- Characteristics of a Cohort of 1300 Patients.mp4
• Merkel Cell Carcinoma in France- Characteristics of a Cohort of 1300 Patients.pdf
• MJ2207 CME Questions Monday with ANSWERS.pdf
• MJ2207 CME Questions Monday.pdf
• MJ2207 CME Questions Tuesday with ANSWERS.pdf
• MJ2207 CME Questions Tuesday.pdf
• Neoadjuvant PD-1 Pathway Blockade for MCC- a window into treatment response and primary resistance.mp4
• Neoadjuvant PD-1 Pathway Blockade for MCC- a window into treatment response and primary resistance.pdf
• Q&A Summary.pdf
• Randomized Phase II Study of NIVO + IPI vs. NIVO + IPI + SBRT in Metastatic or Recurrent Merkel Cell Carcinoma.mp4
• Randomized Phase II Study of NIVO + IPI vs. NIVO + IPI + SBRT in Metastatic or Recurrent Merkel Cell Carcinoma.pdf
• Real world management of MCC patients in France.mp4
• Real world management of MCC patients in France.pdf
• Registration & Breakfast.pdf
• Role of radiotherapy in Merkel cell cancer.mp4
• Role of radiotherapy in Merkel cell cancer.pdf
• State of the Field- Merkel Cell Carcinoma.pdf
• Surgery – Adjuvant RT.mp4
• Surgery – Adjuvant RT.pdf
• Systemic therapies for metastatic Merkel cell carcinoma.mp4
• Systemic therapies for metastatic Merkel cell carcinoma.pdf
• Transcriptional Responses to Type II Interferon Treatment in Merkel cell carcinoma.mp4
• Transcriptional Responses to Type II Interferon Treatment in Merkel cell carcinoma.pdf
• Update on Australian MCC Clinical Trials.mp4
• Update on Australian MCC Clinical Trials.pdf
• Welcome Remarks & Course Intro.pdf