DocmedED 2025 Rhonda K. Yantiss, M.D. Expert Series – Tips and Tricks for GI Biopsy Interpretation

This teaching activity provides a practical review of current topics in gastrointestinal pathology. Dr. Rhonda Yantiss discusses diagnostic pearls that can help surgical pathologists handling cases from the gastrointestinal tract, as well as the pitfalls to be aware of to avoid misdiagnoses. Topics focus on biopsy interpretation and cover a spectrum of inflammatory conditions, as well as colorectal polyps. Appendiceal neoplasms and colorectal cancer staging issues are also addressed.

This activity is primarily intended and designed to educate pathologists.

Educational Symposia

At the completion of this teaching activity, you should be able to:

• Discuss iatrogenic forms of gastrointestinal tract injury.
• Recognize, assess and diagnose colorectal polyps.
• Develop a differential diagnosis for the malabsorptive pattern in duodenal biopsies.
• Distinguish IBD from its mimics.
• Recognize various types of esophageal injury in biopsy samples.
• Develop an approach to patterns of gastric injury.
• Identify key features that aid pathologic assessment of colorectal carcinomas.
• Understand the classification of appendiceal neoplasms
• Formulate a differential diagnosis for mass-forming lesions of the anus.